Detalhe da pesquisa
1.
A selective small-molecule STAT5 PROTAC degrader capable of achieving tumor regression in vivo.
Nat Chem Biol
; 19(6): 703-711, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36732620
2.
A gastrointestinal locally activating Janus kinase inhibitor to treat ulcerative colitis.
J Biol Chem
; 299(12): 105467, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37979913
3.
In Vitro Predictive Dissolution Test Should Be Developed and Recommended as a Bioequivalence Standard for the Immediate-Release Solid Oral Dosage Forms of the Highly Variable Mycophenolate Mofetil.
Mol Pharm
; 19(7): 2048-2060, 2022 07 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35603895
4.
Structure-Activity relationship of 1-(Furan-2ylmethyl)Pyrrolidine-Based Stimulation-2 (ST2) inhibitors for treating graft versus host disease.
Bioorg Med Chem
; 71: 116942, 2022 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35930851
5.
Combined p53- and PTEN-deficiency activates expression of mesenchyme homeobox 1 (MEOX1) required for growth of triple-negative breast cancer.
J Biol Chem
; 295(34): 12188-12202, 2020 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32467227
6.
Carboxypeptidase A4 negatively correlates with p53 expression and regulates the stemness of breast cancer cells.
Int J Med Sci
; 18(8): 1753-1759, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33746592
7.
Albumin Nanoparticle of Paclitaxel (Abraxane) Decreases while Taxol Increases Breast Cancer Stem Cells in Treatment of Triple Negative Breast Cancer.
Mol Pharm
; 17(7): 2275-2286, 2020 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32485107
8.
Synthesis and structure-activity relationships of thieno[2,3-d]pyrimidines as atypical protein kinase C inhibitors to control retinal vascular permeability and cytokine-induced edema.
Bioorg Med Chem
; 28(11): 115480, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32327351
9.
Application of an innovative high-throughput liquid chromatography-tandem mass spectrometry method for simultaneous analysis of 18 hazardous drugs to rule out accidental acute chemotherapy exposures in health care workers.
J Oncol Pharm Pract
; 26(4): 794-802, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-31483750
10.
Liposomal formulation of HIF-1α inhibitor echinomycin eliminates established metastases of triple-negative breast cancer.
Nanomedicine
; 29: 102278, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32738299
11.
Probing the interaction between the histone methyltransferase/deacetylase subunit RBBP4/7 and the transcription factor BCL11A in epigenetic complexes.
J Biol Chem
; 293(6): 2125-2136, 2018 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29263092
12.
Neonatal Fc Receptor (FcRn) Enhances Tissue Distribution and Prevents Excretion of nab-Paclitaxel.
Mol Pharm
; 16(6): 2385-2393, 2019 06 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31002261
13.
MEOX1 Promotes Tumor Progression and Predicts Poor Prognosis in Human Non-Small-Cell Lung Cancer.
Int J Med Sci
; 16(1): 68-74, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30662330
14.
Synthesis of deuterium-labelled amlexanox and its metabolic stability against mouse, rat, and human microsomes.
J Labelled Comp Radiopharm
; 62(5): 202-208, 2019 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30828860
15.
Different Nanoformulations Alter the Tissue Distribution of Paclitaxel, Which Aligns with Reported Distinct Efficacy and Safety Profiles.
Mol Pharm
; 15(10): 4505-4516, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30180593
16.
Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans-Part 2: Fed State.
Mol Pharm
; 15(12): 5468-5478, 2018 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30417648
17.
Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans-Part 1: Fasted State Conditions.
Mol Pharm
; 15(12): 5454-5467, 2018 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30372084
18.
Optimization of dipeptidic inhibitors of cathepsin L for improved Toxoplasma gondii selectivity and CNS permeability.
Bioorg Med Chem Lett
; 28(10): 1972-1980, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29650289
19.
Multibuilding Block Janus Synthesized by Seed-Mediated Self-Assembly for Enhanced Photothermal Effects and Colored Brownian Motion in an Optical Trap.
Small
; 13(6)2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-27873448
20.
Targeting deubiquitinase activity with a novel small-molecule inhibitor as therapy for B-cell malignancies.
Blood
; 125(23): 3588-97, 2015 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-25814533